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ICD-10: E28.2 Medically Verified

Polycystic Ovary Syndrome (PCOS)

Medically reviewed by the SEDU Clinical Review Board. Detailed pathophysiology, symptoms, and care guidelines.

Clinical Overview

A highly common endocrine-metabolic disorder characterized by chronic anovulation, hyperandrogenism (excess male hormones), and micro-cystic appearance of the ovaries.

Associated Symptoms

  • Irregular Menstrual Cycles
  • Menorrhagia (Heavy Menstrual Bleeding)
  • Severe Abdominal Bloating (Endo Belly)

Treatment Pathways

  • Combined Oral Contraceptive Pill
  • Lifestyle & Anti-Inflammatory Diet

Causes & Mechanisms

Complex multifactorial disorder linked to insulin resistance, excess LH secretion, and genetic predisposition resulting in ovarian follicle arrest.

Risk Factors

Insulin resistanceObesitySedentary lifestyleMaternal history of PCOS

Diagnosis & Screening

Diagnosed using the Rotterdam Criteria (requires 2 of 3: irregular cycles, hyperandrogenism, or polycystic ovaries on ultrasound).

Prevention & Care Guidelines

Managed via low-glycemic nutrition, resistance exercise, Metformin, or cycle-suppressing hormones.

Frequently Asked Questions

Q:Can I get pregnant with PCOS?

Yes. With lifestyle planning or ovulation induction support, most people with PCOS can successfully conceive.

Clinical References & Journals

  • 1Rotterdam Consensus Criteria for PCOS Diagnosis, 2003.
  • 2Endocrine Society Clinical Practice Guidelines on PCOS, 2013.