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ICD-10: D25 Medically Verified
Uterine Fibroids (Leiomyomas)
Medically reviewed by the SEDU Clinical Review Board. Detailed pathophysiology, symptoms, and care guidelines.
Clinical Overview
Non-cancerous (benign) tumors of the uterine muscle wall that can range in size from tiny seedlings to bulky masses, causing heavy menstrual bleeding and pressure.
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Associated Symptoms
- Menorrhagia (Heavy Menstrual Bleeding)
- Pelvic Heaviness & Fullness
- Chronic Pelvic Pain
- Urinary Urgency & Frequency
Treatment Pathways
- Myomectomy (Fibroid Removal Surgery)
- Combined Oral Contraceptive Pill
- Lifestyle & Anti-Inflammatory Diet
Causes & Mechanisms
Monoclonal proliferation of smooth muscle cells, heavily influenced by estrogen and progesterone receptor sensitivity and extracellular matrix deposition.
Risk Factors
African ancestryFamily history of fibroidsObesityEarly onset of puberty
Related Conditions
Clinical References & Journals
- 1NIH Fibroids Research Bulletin, 2022.
- 2ACOG Practice Bulletin N.228 on Leiomyomas.